Bioequivalence and Bioavailability Forum

PHX/WNL vs. SAS Proc Mixed [Regulatives / Guidelines]

posted by ElMaestro  – Denmark, 2011-10-10 21:53 (5374 d 05:23 ago) – Posting: # 7463
Views: 16,375

Dear HS,

❝ THX for the comparison! I guess Pharsight will add a note to the manual. PHX/WNL users will learn to life with many lines of "not estimable" in the output if all effects are fixed.

Fortunately you can get rid of a lot of those "not estimable"s. There are two kinds of "not estimable" in play. Those effects which exist but whose addition does not increase the rank of the model matrix (e.g. column for treatment 2 is the intercept minus treatment 1; hence loss of a treatment df) and those which simply don't exist. The former is trivial, the latter should be trivial and easily avoided because subjects are uniquely coded but it seems certain bad habits are difficult to get rid of

EM.

Complete thread:

• Least Square Means (LSM) for unequal sequence yicaoting 2011-10-03 14:37 [Regulatives / Guidelines] 
  • Least Square Means (LSM) for unequal sequence ElMaestro 2011-10-03 14:51
    • Least Square Means (LSM) for unequal sequence yicaoting 2011-10-03 15:28
      • Least Square Means (LSM) for unequal sequence ElMaestro 2011-10-03 15:36
      • Least Square Means (LSM) for unequal sequence Helmut 2011-10-03 16:14
        • Least Square Means (LSM) for unequal sequence ElMaestro 2011-10-03 20:10
    • Least Square Means (LSM) for unequal sequence Pankaj Bhangale 2011-10-04 14:52
      • Weighted Means? Helmut 2011-10-05 01:53
  • LSM for unbalanced sequences -SAS- d_labes 2011-10-04 09:39
    • LSM for unbalanced sequences -SAS- yicaoting 2011-10-04 19:37
      • SE for unbalanced sequences SAS vs. WinNonlin Helmut 2011-10-05 01:01
      • LS Means mean? d_labes 2011-10-05 12:45
        • LS Means mean? ElMaestro 2011-10-05 13:23
        • PHX/WNL vs. SAS Helmut 2011-10-08 02:21
          • PHX/WNL vs. SAS Proc Mixed d_labes 2011-10-10 15:46
            • PHX/WNL vs. SAS Proc Mixed Helmut 2011-10-10 16:30
              • PHX/WNL vs. SAS Proc MixedElMaestro 2011-10-10 19:53
          • Real mixed effects in WNL, SAS, GLM or Mixed (1) yicaoting 2011-10-13 18:39
          • Real mixed effects in WNL, SAS, GLM or Mixed (2) yicaoting 2011-10-13 18:52
          • Real mixed effects in WNL, SAS, GLM or Mixed (3) yicaoting 2011-10-13 19:05
            • Must admit I am lost ElMaestro 2011-10-14 00:02
              • Must admit I am lost yicaoting 2011-10-14 06:30
                • Must admit I am lost - edited ElMaestro 2011-10-14 13:23