Bioequivalence and Bioavailability Forum • PHX/WNL vs. SAS Proc Mixed

PHX/WNL vs. SAS Proc Mixed [Regulatives / Guidelines]

posted by Helmut – Vienna, Austria, 2011-10-10 18:30 (4958 d 11:57 ago) – Posting: # 7460
Views: 13,947

Dear D. Labes,

THX for the comparison! I guess Pharsight will add a note to the manual. PHX/WNL users will learn to life with many lines of "not estimable" in the output if all effects are fixed. ;-)


   Effect:Level  Estimate   StdError Denom_DF T_stat   P_value  Conf T_crit  Lower_CI Upper_CI

----------------------------------------------------------------------------------------------

           int   5.21057    0.108907    14   47.8442    0.0000   95   2.145   4.977   5.444

    sequence:1   0.297533   0.144071    14    2.06519   0.0579   95   2.145  -0.01147 0.6065

    sequence:2    Not estimable

 formulation:1   0.00907183  0.0513393  14    0.176703  0.8623   95   2.145  -0.101   0.1192

 formulation:2    Not estimable

      period:1    -0.0594768 0.0513393  14   -1.1585    0.2660   95   2.145  -0.1696  0.05064

      period:2    Not estimable

sequence:1 sub:1  Not estimable

sequence:1 sub:2   0.329324  0.144071   14    2.28585   0.0384   95   2.145   0.02032 0.6383

sequence:1 sub:3   Not estimable

sequence:1 sub:4   0.0397345 0.144071   14    0.275799  0.7867   95   2.145  -0.2693  0.3487

sequence:1 sub:5  -0.069249  0.144071   14   -0.48066   0.6382   95   2.145  -0.3782  0.2398

sequence:1 sub:6  Not estimable

sequence:1 sub:7  Not estimable

sequence:1 sub:8  -0.114557 0.144071    14   -0.795141  0.4398   95   2.145  -0.4236  0.1944

sequence:1 sub:9  Not estimable

sequence:1 sub:10  Not estimable

sequence:1 sub:11  Not estimable

sequence:1 sub:12 -0.087693 0.144071    14   -0.60868   0.5525   95   2.145  -0.3967  0.2213

sequence:1 sub:13 -0.087512 0.144071    14   -0.607424  0.5533   95   2.145  -0.3965  0.2215

sequence:1 sub:14 Not estimable

sequence:1 sub:15 Not estimable

sequence:1 sub:17 Not estimable

sequence:2 sub:1   0.362241 0.144071    14    2.51432   0.0248   95   2.145   0.05324 0.6712

sequence:2 sub:2  Not estimable

sequence:2 sub:3   0.56588  0.144071    14    3.92779   0.0015   95   2.145   0.2569  0.8749

sequence:2 sub:4  Not estimable

sequence:2 sub:5  Not estimable

sequence:2 sub:6   0.216567 0.144071    14    1.5032    0.1550   95   2.145  -0.09243 0.5256

sequence:2 sub:7  -0.008024 0.144071    14   -0.0556949 0.9564   95   2.145  -0.317   0.301

sequence:2 sub:8  Not estimable

sequence:2 sub:9   0.182748 0.144071    14    1.26846   0.2253   95   2.145  -0.1263  0.4917

sequence:2 sub:10  0.324924 0.144071    14    2.25531   0.0406   95   2.145   0.01592 0.6339

sequence:2 sub:11 -0.18342  0.144071    14   -1.27313   0.2237   95   2.145  -0.4924  0.1256

sequence:2 sub:12 Not estimable

sequence:2 sub:13 Not estimable

sequence:2 sub:14  0.271593 0.144071    14    1.88513   0.0803   95   2.145  -0.03741 0.5806

sequence:2 sub:15  Not estimable

sequence:2 sub:17  Not estimable

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz

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Complete thread:

Least Square Means (LSM) for unequal sequence yicaoting 2011-10-03 14:37 [Regulatives / Guidelines]
- Least Square Means (LSM) for unequal sequence ElMaestro 2011-10-03 14:51
  - Least Square Means (LSM) for unequal sequence yicaoting 2011-10-03 15:28
    - Least Square Means (LSM) for unequal sequence ElMaestro 2011-10-03 15:36
    - Least Square Means (LSM) for unequal sequence Helmut 2011-10-03 16:14
      - Least Square Means (LSM) for unequal sequence ElMaestro 2011-10-03 20:10
  - Least Square Means (LSM) for unequal sequence Pankaj Bhangale 2011-10-04 14:52
    - Weighted Means? Helmut 2011-10-05 01:53
- LSM for unbalanced sequences -SAS- d_labes 2011-10-04 09:39
  - LSM for unbalanced sequences -SAS- yicaoting 2011-10-04 19:37
    - SE for unbalanced sequences SAS vs. WinNonlin Helmut 2011-10-05 01:01
    - LS Means mean? d_labes 2011-10-05 12:45
      - LS Means mean? ElMaestro 2011-10-05 13:23
      - PHX/WNL vs. SAS Helmut 2011-10-08 02:21
        
        PHX/WNL vs. SAS Proc Mixed d_labes 2011-10-10 15:46
        
        PHX/WNL vs. SAS Proc MixedHelmut 2011-10-10 16:30
        
        PHX/WNL vs. SAS Proc Mixed ElMaestro 2011-10-10 19:53
        
        Real mixed effects in WNL, SAS, GLM or Mixed (1) yicaoting 2011-10-13 18:39
        Real mixed effects in WNL, SAS, GLM or Mixed (2) yicaoting 2011-10-13 18:52
        Real mixed effects in WNL, SAS, GLM or Mixed (3) yicaoting 2011-10-13 19:05
        
        Must admit I am lost ElMaestro 2011-10-14 00:02
        
        Must admit I am lost yicaoting 2011-10-14 06:30
        
        Must admit I am lost - edited ElMaestro 2011-10-14 13:23