Bioequivalence and Bioavailability Forum • LSM for unbalanced sequences -SAS-

LSM for unbalanced sequences -SAS- [Regulatives / Guidelines]

posted by d_labes – Berlin, Germany, 2011-10-04 11:39 (4964 d 17:45 ago) – Posting: # 7420
Views: 15,386

Dear yicaoting,

❝ I have tried to analysis this unequal sequences data in SAS and Stata, both were failed.

❝

❝ In SAS, I used the following code:

❝ ...

❝ It returned:

❝ ERROR: One or more variables are missing or freq or weight is zero on every observation.

❝ 182 quit;

Sorry but I can't reproduce your Error(neous) result utilizing SAS 9.2.
Using your data and your code (exactly as given above by you) all goes fine and I get for the LSM section:


Least Squares Means



                               H0:LSMean1=

                     logAUC      LSMean2

formulation          LSMEAN       Pr > |t|

1                5.43564048         0.8623

2                5.42656865





                     logAUC

formulation          LSMEAN      90% Confidence Limits

1                  5.435640        5.371701     5.499580

2                  5.426569        5.362629     5.490508





     Least Squares Means for Effect formulation



            Difference

               Between    90% Confidence Limits for

i    j           Means       LSMean(i)-LSMean(j)

1    2        0.009072       -0.081353     0.099496

So, what did you do here :confused:

Check your variables. The error occurred hints to a left hand variable in the model which has only missing values everywhere.

BTW: We had already several discussions here on unbalanced / incomplete data. See for instance this thread. But be warned: Rather lengthy and nitpicking :-D

—
Regards,

Detlew

Complete thread:

Least Square Means (LSM) for unequal sequence yicaoting 2011-10-03 14:37 [Regulatives / Guidelines]
- Least Square Means (LSM) for unequal sequence ElMaestro 2011-10-03 14:51
  - Least Square Means (LSM) for unequal sequence yicaoting 2011-10-03 15:28
    - Least Square Means (LSM) for unequal sequence ElMaestro 2011-10-03 15:36
    - Least Square Means (LSM) for unequal sequence Helmut 2011-10-03 16:14
      - Least Square Means (LSM) for unequal sequence ElMaestro 2011-10-03 20:10
  - Least Square Means (LSM) for unequal sequence Pankaj Bhangale 2011-10-04 14:52
    - Weighted Means? Helmut 2011-10-05 01:53
- LSM for unbalanced sequences -SAS-d_labes 2011-10-04 09:39
  - LSM for unbalanced sequences -SAS- yicaoting 2011-10-04 19:37
    - SE for unbalanced sequences SAS vs. WinNonlin Helmut 2011-10-05 01:01
    - LS Means mean? d_labes 2011-10-05 12:45
      - LS Means mean? ElMaestro 2011-10-05 13:23
      - PHX/WNL vs. SAS Helmut 2011-10-08 02:21
        
        PHX/WNL vs. SAS Proc Mixed d_labes 2011-10-10 15:46
        
        PHX/WNL vs. SAS Proc Mixed Helmut 2011-10-10 16:30
        
        PHX/WNL vs. SAS Proc Mixed ElMaestro 2011-10-10 19:53
        
        Real mixed effects in WNL, SAS, GLM or Mixed (1) yicaoting 2011-10-13 18:39
        Real mixed effects in WNL, SAS, GLM or Mixed (2) yicaoting 2011-10-13 18:52
        Real mixed effects in WNL, SAS, GLM or Mixed (3) yicaoting 2011-10-13 19:05
        
        Must admit I am lost ElMaestro 2011-10-14 00:02
        
        Must admit I am lost yicaoting 2011-10-14 06:30
        
        Must admit I am lost - edited ElMaestro 2011-10-14 13:23