Dissolution similarity [Dissolution / BCS / IVIVC]
Hi,
As this question comes up from time to time, I found the following reference: http://wenku.baidu.com/view/01246164783e0912a2162a08.html
I'll write a function in R, but I'm short in time for the moment.
Maybe after the weekend.
Good luck
Ace
PS: for those who want to play with the data in R:
As this question comes up from time to time, I found the following reference: http://wenku.baidu.com/view/01246164783e0912a2162a08.html
I'll write a function in R, but I'm short in time for the moment.
Maybe after the weekend.
Good luck
Ace
PS: for those who want to play with the data in R:
m.ref <-
structure(list(V1 = c(42.06, 44.16, 45.63, 48.52, 50.49, 49.77
), V2 = c(59.91, 60.18, 55.77, 60.39, 61.82, 62.73), V3 = c(65.58,
67.17, 65.56, 66.51, 69.06, 69.77), V4 = c(71.81, 70.82, 70.5,
73.06, 72.85, 72.88), V5 = c(77.77, 76.11, 76.92, 78.54, 78.99,
80.18), V6 = c(85.67, 83.27, 83.91, 84.99, 86.86, 84.2), V7 = c(93.14,
88.01, 86.83, 88, 89.7, 88.88), V8 = c(94.23, 89.59, 90.12, 93.43,
90.79, 90.47)), .Names = c("V1", "V2", "V3", "V4", "V5", "V6",
"V7", "V8"), class = "data.frame", row.names = c(NA, -6L))
m.test <-
structure(list(V1 = c(19.99, 22.08, 21.93, 22.44, 25.67, 26.37
), V2 = c(36.7, 39.29, 38.54, 39.46, 42.35, 41.34), V3 = c(47.77,
49.46, 47.76, 49.72, 52.68, 51.01), V4 = c(55.08, 56.79, 55.14,
58.67, 59.71, 57.75), V5 = c(65.69, 67.22, 65.25, 69.21, 71.51,
69.44), V6 = c(81.37, 82.42, 83.49, 84.93, 86.61, 85.9), V7 = c(92.39,
89.93, 90.19, 94.12, 93.8, 94.45), V8 = c(97.1, 95.62, 95.62,
95.51, 96.7, 98.07)), .Names = c("V1", "V2", "V3", "V4", "V5",
"V6", "V7", "V8"), class = "data.frame", row.names = c(NA, -6L
))
cov(m.ref) #Variance-covariance matrix of reference
cov(m.test) #Variance-covariance matrix of test
Complete thread:
- Dissolution similarity Nirali 2010-11-10 11:13 [Dissolution / BCS / IVIVC]
- Dissolution similarity Nirali 2011-04-21 12:27
- Dissolution similarityAceto81 2011-04-28 15:14
- Mahalanobis distance - R code d_labes 2011-04-29 15:14
- Dissolution similarityAceto81 2011-04-28 15:14
- DDSolver, Mahalanobis distance and its 90% CI yicaoting 2011-10-06 16:03
- DDSolver, Mahalanobis distance and its 90% CI Nirali 2012-07-03 07:40
- DDSolver, Mahalanobis distance and its 90% CI d_labes 2012-07-06 10:54
- DDSolver, Mahalanobis distance and its 90% CI Sid 2019-03-07 19:23
- Dissolution similarity Nirali 2011-04-21 12:27