Subtleties, flaws, questions [BE/BA News]

posted by Helmut Homepage – Vienna, Austria, 2011-03-27 22:35 (4380 d 01:07 ago) – Posting: # 6818
Views: 32,392

Dear D. Labes!

Source         DF   Type III SS   Mean Square  [...]

sequence        0    0.0000000    .            [...]


Zero degrees of freedom is not a lot.
I love SAS‘s ‘.’ - Phoenix/WinNonlin spits out ‘Not estimable’, but I can trim it to ‘.’ or even ‘0’… :-D

Open issues IMHO:
  • Outliers – which method? Model residuals or R/R ratios?
  • Obviously EMA is not interested in CVWT (Method C) at all. Since GLM throws away incomplete data (Method A), why should one go with a full replicate design? More periods, more chances of drop-outs.

Dif-tor heh smusma 🖖🏼 Довге життя Україна! [image]
Helmut Schütz

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

UA Flag
 Admin contact
22,550 posts in 4,724 threads, 1,606 registered users;
16 visitors (0 registered, 16 guests [including 9 identified bots]).
Forum time: 22:43 CET (Europe/Vienna)

That which is static and repetitive is boring.
That which is dynamic and random is confusing.
In between lies art.    John Locke

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz