gender specific generics? [Surveys]
Dear ElMaestro
dear all
I just evaluated the second study with the same compound/dose/nearly identical formulation.
Evaluation with the whole study population => bioequivalent
Subgroups:
males => AUC bioequivalent
females => AUC bioequivalent
90% confidence intervals for AUC for males and females have no overlap
(99-121 vs 83-95)
90% confidence intervals for Cmax for males and females congruent.
Is this just a statistical artefact?
Looking forward to your reply
Kind regards
Dan
dear all
I just evaluated the second study with the same compound/dose/nearly identical formulation.
Evaluation with the whole study population => bioequivalent
Subgroups:
males => AUC bioequivalent
females => AUC bioequivalent
90% confidence intervals for AUC for males and females have no overlap
(99-121 vs 83-95)
90% confidence intervals for Cmax for males and females congruent.
Is this just a statistical artefact?
Looking forward to your reply
Kind regards
Dan
—
Kind regards and have a nice day
Dr_Dan
Kind regards and have a nice day
Dr_Dan
Complete thread:
- gender specific generics? Dr_Dan 2011-02-17 10:34
- gender specific generics? ElMaestro 2011-02-17 13:54
- gender specific generics? Dr_Dan 2011-02-17 15:09
- gender specific generics? ElMaestro 2011-02-17 15:44
- gender specific generics?Dr_Dan 2011-03-11 15:24
- gender specific generics? Helmut 2011-03-11 15:32
- gender specific generics? ElMaestro 2011-03-11 16:37
- gender specific generics? Dr_Dan 2011-03-14 09:20
- Formulation-by-gender interaction? d_labes 2011-03-14 08:32
- gender specific generics?Dr_Dan 2011-03-11 15:24
- gender specific generics? ElMaestro 2011-02-17 15:44
- gender specific generics? Dr_Dan 2011-02-17 15:09
- gender specific generics? ElMaestro 2011-02-17 13:54