difficult to eliminate a subject [Outliers]

posted by ElMaestro  – Denmark, 2011-03-10 13:20 (4471 d 06:38 ago) – Posting: # 6736
Views: 7,152

Hi SK,

❝ On review of p'cokinetic data it was observed that one of subject is showing highest T/R ratio for Cmax and AUC. So we just recalculate 90% CI by excluding that subject and those results were within acceptance limit. No specific outlier test is applied here.

If you have just pulled out the subject with the highest T/R without any further qualification then that won't be acceptable. If you have confirmed technical issues with the samples then you may be able to take out the subject, same thing if the subject vomited etc.

Pass or fail!

Complete thread:

UA Flag
 Admin contact
22,618 posts in 4,741 threads, 1,611 registered users;
19 visitors (0 registered, 19 guests [including 4 identified bots]).
Forum time: 20:58 CEST (Europe/Vienna)

There are in fact two things, science and opinion;
the former begets knowledge, the latter ignorance.    Hippocrates

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz