Bioequivalence and Bioavailability Forum • Really not?

Really not? [Dissolution / BCS / IVIVC]

posted by Aceto81 – Belgium, 2011-03-02 13:28 (5178 d 05:44 ago) – Posting: # 6683
Views: 13,063

I will take a deeper look at the free solver, looks interesting.

For the f2 calculation, there are some rules on %RSD. If your RSD is too high, you can bootstrap your results to calculate CI on your f2 value.
I must have an R script for this bootstrap, if anyone is interested, I will digg into my harddisk to see if I can find it.

Ace

Complete thread:

Mutivariate test for profile similarity d_labes 2011-02-23 14:47 [Dissolution / BCS / IVIVC]
- Mutivariate test for profile similarity yjlee168 2011-02-24 08:50
  - Mutivariate test for profile similarity d_labes 2011-02-24 15:04
- Mutivariate test for profile similarity Aceto81 2011-02-25 12:33
- Anything (?) else than f2 not acceptable in the EU? Helmut 2011-03-01 13:30
  - Really not? d_labes 2011-03-01 16:07
    - Really not? ElMaestro 2011-03-01 20:02
      - SOPs Helmut 2011-03-02 01:06
      - SOPs d_labes 2011-03-02 08:06
    - Really not?Aceto81 2011-03-02 12:28