Therapeutic equivalence? [Design Issues]
Dear PK,
what therapeutic action of an Anti-cancer agent do you expect in healthy volunteers
?
Due to the cytotoxic effects of most Anti-cancer agents it's IMHO unethically to treat healthy volunteers with them. So also a classical BE study (comparing blood/plasma/serum levels is IMHO also not possible in most cases
.
what therapeutic action of an Anti-cancer agent do you expect in healthy volunteers

Due to the cytotoxic effects of most Anti-cancer agents it's IMHO unethically to treat healthy volunteers with them. So also a classical BE study (comparing blood/plasma/serum levels is IMHO also not possible in most cases

—
Regards,
Detlew
Regards,
Detlew
Complete thread:
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