lmer vs. lme [R for BE/BA]

posted by d_labes  – Berlin, Germany, 2011-01-28 09:02 (3918 d 16:01 ago) – Posting: # 6503
Views: 62,820

Dear ElMaestro!

» I am starting to believe lme does in some cases not really reach the goal, so I switched to lmer (package lme4). Syntactically something like:
» ElModel=lmer(logCmax ~ per+seq+trt + (trt-1|subj))
» -which achieves the same.
Really :ponder:

Using the newer lmer() instead of lme() is another possibility, considered by me also before coming up with my R implementation attempt of the FDA Proc MIXED code. But it lacks the separate estimability of the intra-subject error variance for Test and Reference, I think. As far as I know (from the R help lists) there are no plans to introduce somefink like weights in lmer().
Therefore it is not so useful in the framework of scABE, I think.

I could be wrong, but ... :-D



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