Bioequivalence and Bioavailability Forum

Opinions ... [Design Issues]

posted by d_labes  – Berlin, Germany, 2011-01-07 14:51 (5292 d 00:03 ago) – Posting: # 6402
Views: 17,633

Dear Byung-Ju,

❝ And this other I suggest to my opinion

❝ ...

A man having his own opinion is always preferable .
But as John Moore said: "Your opinion is your opinion, your perception is your perception - do not confuse them them with 'facts' or 'truth' ... " (the rest of this quote may be somewhat bothering).

You are totally right if the point estimator and the CV you have used in your sample size estimation (taken from a particular study - why that and not the PAR studies?) are the true values, are "carved in stone" - Helmut's favourite terminology.

Have a look at this thread for another strong opinion and go through the category "Sample Size" of this forum - discussions of sample size in connection with pilot study.
Eventually are some thoughts mentioned there worth considering them.

Complete thread:

• Montelukast BE study rahul dixit 2011-01-03 15:17 [Design Issues] 
  • Montelukast BE study bjkim97 2011-01-06 06:45
    • Opinions ...d_labes 2011-01-07 13:51
      • Opinions ... bjkim97 2011-01-11 06:47
    • Montelukast BE study joy_fm 2015-02-05 13:10
      • MHRA’s PARs Helmut 2015-02-05 13:24
        • MHRA’s PARs joy_fm 2015-02-10 17:38
          • CV from the CI Helmut 2015-02-11 02:05
            • CI2CV d_labes 2015-02-11 09:16
              • Beyond the abstract Helmut 2015-02-11 13:01
                • Beyond the abstract ElMaestro 2015-02-11 13:36
                  • Beyond the abstract & Kinetica Helmut 2015-02-11 14:27
                    • Beyond the abstract & Kinetica d_labes 2015-02-11 14:59
                      • Partial credit ElMaestro 2015-02-11 15:49
                        • Partial credit ioanam 2016-01-22 14:17
                          • Partial credit ElMaestro 2016-01-22 14:58
                            • Partial credit Helmut 2016-01-22 15:06