Bioequivalence and Bioavailability Forum • Ballpark figure(s)

Ballpark figure(s) [Design Issues]

posted by Helmut – Vienna, Austria, 2010-11-26 13:59 (5690 d 10:37 ago) – Posting: # 6238
Views: 7,502

Dear Kishor!

❝ Is this correct time point for the Drug having Tmax 1 hr and T half 2 hrs as intravenous infusion.

❝ […] 0.00, 0.25, 0.75, 1.00, 1.5, 2.0, 3.0, 4.0, 5.0, 6.0, 8.0, 12.0.

IMHO, no. You may use them (as any others), but they are not optimal.

❝ I hope u will provide the correct time point to me

Sorry, that's not the way it works here. If you tell me how you got your numbers (especially the 8 hrs), we can continue the discussion. If I simply tell you my sampling scheme, will you ask me again for all further studies?

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz

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Complete thread:

Regarding Time point selection of IV infusion formulation kishorpatil 2010-11-22 04:50 [Design Issues]
- Time points (infusion) Helmut 2010-11-22 14:42
  - Time points (infusion) kishorpatil 2010-11-23 10:54
    - NCA = model independent Helmut 2010-11-23 13:57
      - Details time points kishorpatil 2010-11-26 09:35
        
        Ballpark figure(s)Helmut 2010-11-26 12:59
        
        Ballpark figure(s) kishorpatil 2010-11-29 11:41
        
        Believes... Helmut 2010-11-29 13:44
        
        Believes... kishorpatil 2010-11-30 05:56
        
        Are you serious? Helmut 2010-11-30 15:38
        
        Are you serious? kishorpatil 2010-12-09 05:10
      - NCA = model independent NewInPK 2011-01-31 05:47