BE parallel design [General Sta­tis­tics]

posted by Jaime_R – Barcelona, 2007-04-03 20:58 (6204 d 12:51 ago) – Posting: # 617
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Hi PKPDPKPD - what a nick! :cool:

❝ While assessing BE in two-group parallel design study, should one use nominal data or log transformed data.


Log-transformed if you are applying a multiplicative model (for all clearance based parameters, e.g., for AUC, Cmax,...)
Untransformed for Tmax - if applicable to your formulation.

❝ If log transformed, should it be log or ln?


Whatever you like (ld - logarithmus dualis - would also do the job), but most people prefer ln.

Regards, Jaime

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