BE parallel design [General Sta­tis­tics]

posted by Jaime_R – Barcelona, 2007-04-03 18:58 (5409 d 10:38 ago) – Posting: # 617
Views: 15,420

Hi PKPDPKPD - what a nick! :cool:

» While assessing BE in two-group parallel design study, should one use nominal data or log transformed data.

Log-transformed if you are applying a multiplicative model (for all clearance based parameters, e.g., for AUC, Cmax,...)
Untransformed for Tmax - if applicable to your formulation.

» If log transformed, should it be log or ln?

Whatever you like (ld - logarithmus dualis - would also do the job), but most people prefer ln.

Regards, Jaime

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