Blind ? [Two-Stage / GS Designs]

posted by Ohlbe – France, 2010-10-27 23:37 (4103 d 23:42 ago) – Posting: # 6092
Views: 12,253

Dear Jack,

What's probably confusing to a number of people following this thread is what you exactly mean with "blind". In clinical trials this is usually meant as not knowing which treatment is administered to which patient/subject. In a BE trial this usually only applies to the bioanalytical lab. You can't run the statistical analysis without unblinding (even if you call the products A and B and don't tell the statistician which is the test and which is the reference, it won't make any difference).

So to keep it short, a question from a non-statistician: what do you exactly mean by blinded in this particular context ? Blinded to what ?

Regards
Ohlbe

Regards
Ohlbe

Complete thread:

Activity
 Admin contact
21,835 posts in 4,569 threads, 1,554 registered users;
online 5 (0 registered, 5 guests [including 3 identified bots]).
Forum time: Friday 22:19 CET (Europe/Vienna)

No problem can stand the assault of sustained thinking.    Voltaire

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5