Blind ? [Two-Stage / GS Designs]

posted by Ohlbe – France, 2010-10-27 23:37  – Posting: # 6092
Views: 10,248

Dear Jack,

What's probably confusing to a number of people following this thread is what you exactly mean with "blind". In clinical trials this is usually meant as not knowing which treatment is administered to which patient/subject. In a BE trial this usually only applies to the bioanalytical lab. You can't run the statistical analysis without unblinding (even if you call the products A and B and don't tell the statistician which is the test and which is the reference, it won't make any difference).

So to keep it short, a question from a non-statistician: what do you exactly mean by blinded in this particular context ? Blinded to what ?



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