Bioequivalence and Bioavailability Forum

Dear Maura,

I don't own WNL therefore I can't verify your WNL results.
But from the form of output I guess that you have done a mixed model analysis in WNL?

Then the appropriate SAS code will be:
Proc mixed data=maura;
  class seq subj per droga carry;
  model lnasc=seq per droga carry/DDFM=satterth;
  random subj(seq);
run;
This gives among the output:
...
                   The Mixed Procedure

                   Covariance Parameter
                       Estimates

                 Cov Parm      Estimate

                  Subj(SEQ)      0.02788
                  Residual       0.03344
...
             Type 3 Tests of Fixed Effects

                   Num     Den
     Effect         DF      DF    F Value    Pr > F

     Droga           2      18       3.44    0.0543
     Per             2      18       1.27    0.3037
     SEQ             5    6.32       1.56    0.2956
     Carry           2      18       1.21    0.3204

This is very close to your results with Proc GLM, as I had expected.

Thus I can't figure out why WNL gives distinct F-tests.
Check your model specifications and data thoroughly.

Maybe that WNL partial F-tests do not correspond to SAS type III tests? Any of the WNL owners out there with an opinion?

❝ Thanks and sorry about my English!!

(emphasis by me) Welcome to the club.