Bioequivalence and Bioavailability Forum • clopidogrel

clopidogrel [Bioanalytics]

posted by ioanam – Romania, 2010-08-10 17:17 (5781 d 09:50 ago) – Posting: # 5763
Views: 9,453

Dear Ohlbe,

I'm sorry that I did not present very clear my question.

The mean value obtained in the study is around 5 - 6 ng/ml for both products.

Statistical results showed a T/R ratio of almost 1.0, but the study failed for Cmax (using 80 - 125%) and EMA does not approve to wide 90% IC for clopidogrel.
I still can't explain those increased values for Cmax.

I have to find if there is a mistake in this study, where to find it.

Kindest regards,
Ioanam

Complete thread:

clopidogrel ioanam 2010-08-10 10:42 [Bioanalytics]
- clopidogrel Dr_Dan 2010-08-10 11:21
  - clopidogrel ioanam 2010-08-10 11:28
  - clopidogrel ioanam 2010-08-10 11:43
    - clopidogrel Ohlbe 2010-08-10 12:17
- clopidogrel ioanam 2010-08-10 14:13
  - clopidogrel Ohlbe 2010-08-10 14:59
    - clopidogrelioanam 2010-08-10 15:17
      - clopidogrel Ohlbe 2010-08-10 16:12
        
        clopidogrel ioanam 2010-08-10 18:34
        
        clopidogrel Dr_Dan 2010-08-11 09:24
        
        clopidogrel ioanam 2010-08-11 11:08
        
        clopidogrel Ohlbe 2010-10-05 00:06