Phoenix/WinNonlin-experts around? [General Sta­tis­tics]

posted by d_labes  – Berlin, Germany, 2010-07-13 14:15 (5421 d 17:36 ago) – Posting: # 5615
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Dear Helmut!

❝ I got:

Warning 11091: Newton's algorithm converged with modified Hessian.

Output is suspect.

Model may be over-specified. A simpler model could be tried.

❝ and sigma²WR 0.1861995 (CVWR 0.452397)


This is the continuation of our earlier discussion: The FDA model (and your specification is some sort of :yes:) is over-specified for the extra-reference design.

Regards,

Detlew

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