Bioequivalence and Bioavailability Forum

SAS and/or Phoenix/WinNonlin-experts around? [General Sta­tis­tics]

posted by Helmut  – Vienna, Austria, 2010-07-13 04:29 (5817 d 05:48 ago) – Posting: # 5613
Views: 17,006

Dear Paolo!

Had a quick look in Phoenix6.1 (average BE, too late to get FDA's model running).
Fixed: SEQUENCE+TREATMEN+PERIOD
Repeated Specification:
PERIOD
Variance Blocking Variables (Subject): SUBJECT
Group: TREATMEN
Type: Variance Components
Random Effects: TREATMEN
Variance Blocking Variables (Subject): SUBJECT
Type: Banded No-Diagonal Factor Analytic (f)
Number of factors (f): 2

I got:
Warning 11091: Newton's algorithm converged with modified Hessian. Output is suspect.
Model may be over-specified. A simpler model could be tried.
and sigma²_WR 0.1861995 (CV_WR 0.452397)

If I try IBE/PBE I got:
*** WARNING 11121: Subject X had incomplete design and was discarded.
*** WARNING 11122: Sequence RTR had less than two complete subjects and was discarded.
*** WARNING 11122: Sequence TRR had less than two complete subjects and was discarded.
*** ERROR 11107: Fewer than two sequences had complete design. Program termininating.
X in the warning above is the ID of all subjects except ones in sequence RRT. That was it.

---

P.S.: Please delete anything from the text of the original poster which is not necessary in understanding your answer; see also this post!

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна! 
Helmut Schütz


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Science Quotes

Complete thread:

• SABE Reference Variability and CI Computation preyes323 2010-07-12 17:12 [General Sta­tis­tics] 
  • Dataset Helmut 2010-07-12 17:26
    • Dataset preyes323 2010-07-12 18:20
      • Data format Helmut 2010-07-12 18:38
        • Data format preyes323 2010-07-13 01:16
          • SAS and/or Phoenix/WinNonlin-experts around?Helmut 2010-07-13 02:29
            • Phoenix/WinNonlin-experts around? d_labes 2010-07-13 12:15
              • Phoenix/WinNonlin-experts around? Helmut 2010-07-13 13:42
                • Mixed interest d_labes 2010-07-13 15:11
                  • Mixed interest Helmut 2010-07-13 19:19
                    • lme() answer and beyond ... d_labes 2010-07-14 10:41
                      • lme() answer and beyond ... Helmut 2010-07-14 13:47
                        • AIC, BIC and that all ... d_labes 2010-07-15 12:01
          • To Err is Human d_labes 2010-07-13 11:51
            • To Err is Human, but... Helmut 2010-07-13 13:45
              • ... to Arr is Pirate d_labes 2010-07-13 15:47
                • Brilliant page!!! ElMaestro 2010-07-14 21:03
            • To Err is Human preyes323 2010-07-14 14:45
              • Heads up! Helmut 2010-07-14 15:17
              • To Err is Teacher d_labes 2010-07-15 11:05
            • To Err is Human preyes323 2010-07-16 02:28
              • To Err is Human d_labes 2010-07-16 10:42
                • To Err is Human preyes323 2010-07-17 11:14
                  • Regulatory constants d_labes 2010-07-19 10:00
          • Data format ElMaestro 2011-02-06 11:54
            • SAS System Viewer Helmut 2011-02-06 13:02