Bioequivalence and Bioavailability Forum • NTIDs # HVDs (or not?)

NTIDs # HVDs (or not?) [Design Issues]

posted by Dr_Dan – Germany, 2010-06-08 14:24 (5864 d 02:05 ago) – Posting: # 5468
Views: 10,733

Hi Helmut

❝ If we are talking about immunosuppressants, we are talking about a study in patients, right? Steady state too. Likely parallel design – it’s unethical to interrupt treatment by a washout.

If you investigate steady state PK you can do an "active washout" without interrupting treatment.

Regards
Dan

—
Kind regards and have a nice day
Dr_Dan

Complete thread:

NTIDs with high variability ioanam 2010-06-07 13:52 [Design Issues]
- NTIDs # HVDs (or not?) Helmut 2010-06-07 14:18
  - NTIDs # HVDs (or not?) ioanam 2010-06-07 18:17
    - Complicated ElMaestro 2010-06-07 18:28
  - NTIDs # HVDs (or not?)Dr_Dan 2010-06-08 12:24
    - Switch over Helmut 2010-06-08 12:34
      - NTIDs # HVDs (or not?) Relaxation 2010-06-09 22:38
        
        FDA scaling for NTIDs krishna 2013-01-07 14:01
        
        FDA scaling for NTIDs Helmut 2013-01-12 20:06
        
        FDA scaling for NTIDs krishna 2013-01-18 10:04
        
        FDA scaling for NTIDs Helmut 2013-01-20 12:46
        
        FDA scaling for NTIDs krishna 2013-02-01 12:20