Bioequivalence and Bioavailability Forum • IVIVC Studies

IVIVC Studies [Dissolution / BCS / IVIVC]

posted by Helmut – Vienna, Austria, 2007-02-07 20:56 (6454 d 23:28 ago) – Posting: # 510
Views: 42,077

Dear Mamidi!

❝ Please tell me about how to proceed for IVIVC using the pilot data.

OK, you are going in the right direction, namely starting with in vivo data!

❝ Also can anybody tell me the important tests and procedure for IVIVC Studies using WinNonlin or any software (SAS, SPSS,.....).

Unless you want to start with parametric deconvolution, even M$-Excel will do the job (I would not trust the built-in Solver-routine)…
Kinetica offers templates for the ‘classical’ methods (Wagner-Nelson, Loo-Riegelman) and convolution/deconvolution.
If you have already a little experience with WinNonlin’s programming language, it should not be too difficult to implement any needed model manually.
An additional product (the IVIVC Tookit) is available for the latest release (5.2) of WinNonlin only.

❝ If there are any important sites regarding IVIVC kindly let me know.

Not directly IVIVC, but browse through the archive at Dissolution Technologies, and have a look at this nice review.

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Complete thread:

IVIVC Studies MGR 2007-02-02 10:10
- IVIVC StudiesHelmut 2007-02-07 19:56
  - IVIVC Studies venu 2007-02-23 06:58
    - IVIVC Studies Dipesh Jayswal 2007-03-16 07:53
      - Wagner-Nelson, Loo-Riegelman Helmut 2007-03-16 15:39
        
        Wagner-Nelson, Loo-Riegelman Dipesh Jayswal 2007-03-19 10:04
        Deconvolution drcampos 2007-03-19 15:26
        
        Numerical Deconvolution Helmut 2007-03-19 16:20
        
        Numerical Deconvolution drcampos 2007-03-19 21:17
        Numerical Deconvolution Rayhope 2021-10-07 14:25
        
        Daniel still active in the Forum? Helmut 2021-10-07 16:38
        
        Daniel still active in the Forum? Rayhope 2021-10-08 09:07
        
        Daniel still active in the Forum? Rayhope 2021-11-11 08:35
        
        Wagner-Nelson Dipesh Jayswal 2007-03-21 08:21
        
        Wagner-Nelson Helmut 2007-03-21 12:13
        
        IVIVC jesse08 2007-09-01 01:38
        
        IVIVC / Mapping Helmut 2007-09-01 14:49
        
        IVIVC / Mapping jesse08 2007-09-02 00:32
        
        IVIVC / Software Helmut 2007-09-02 12:03
        
        IVIVC / Software jesse08 2007-10-03 02:13
        
        IVIVC / Software Nirali 2007-11-21 12:38
        
        at least 3 formulations for IVIVC Helmut 2007-11-21 15:25
        
        at least 3 formulations for IVIVC Nirali 2007-11-22 07:53
        
        at least 1 formulation for Level A Helmut 2007-11-22 09:53
        
        at least 1 formulation for Level A Nirali 2007-11-27 06:05
        
        IVIVC / Software SDavis 2009-09-25 09:11
        
        IVIVC set up/ requirements sonu 2009-09-23 08:47