Bioequivalence and Bioavailability Forum

Some youngsters may be very old [Software]

posted by d_labes  – Berlin, Germany, 2010-04-12 11:39 (5548 d 03:23 ago) – Posting: # 5082
Views: 19,466

Mark Twain: "Age is an issue of mind over matter. If you don't mind, it doesn't matter."

Dear Helmut!

❝ Oh, TopFit (like billards it required a combination of imagination, skill, patience, and devotion). I wouldn’t call it a dinosaur - at sweet seventeen has not reached adolescence yet.

Seventeen is rather young for NLYW but may be very old for software.
Considering the life cycles of some other pieces of software (1993: M$-W for Workgroups 3.11, 1994: M$-W NT Workstation 3.5, 1995: M$-W 95, 1996: M$-W NT Workstation 4.0, 1998: M$-W 98, 1999: M$-W 98 SE, and so on, and so on ...) I estimate that TopFit had now reached at least version 18.0 .

Unfortunately it had not evolved after 1993 but for me it was very useful up to the year 2007 (!) as the main NCA tool. So my judgment is that it was adolescent and reliable from the beginning.

Complete thread:

• Pk parameter: Urine study (WinNonlin) AA 2010-04-07 07:01 [Software] 
  • Ae-inf based on rate Helmut 2010-04-07 18:26
    • Ae-inf based on rate AA 2010-04-08 14:08
      • Amount_ Recovered = Ae(0-t) Helmut 2010-04-08 14:27
    • Already a PK-model? H_Rotter 2010-04-08 20:07
      • Already a PK-model? Helmut 2010-04-08 20:47
        • Dinosaurs solution. d_labes 2010-04-09 09:31
          • Youngster's solution Helmut 2010-04-09 17:25
            • Some youngsters may be very oldd_labes 2010-04-12 09:39
    • Ae-inf based on rate SDavis 2010-04-09 13:10
      • Replicate design studies in Phoenix/WinNonlin Helmut 2010-04-09 17:47