Bioequivalence and Bioavailability Forum

Yes, but... [General Sta­tis­tics]

posted by Helmut  – Vienna, Austria, 2010-04-10 16:46 (5910 d 18:17 ago) – Posting: # 5076
Views: 10,515

Ahoi!

❝ Just re-read your post - you are suggesting exactly the same if I interpret your post right?

Yes. After RTFM and setting up the model with a study × period interaction term, I'm getting exactly the same results as with faked four periods.

There are only minor differences between the 'faked 4 period' and interaction set-ups, probably due to numerical issues. More significant digits below:
Faked Periods:  95.1926% (91.1103% - 99.4578%), CVintra 9.02706%
Period × Study: 95.1915% (91.1007% - 99.4660%), CVintra 9.04355%

Apart from the technical issues, my main concern remains alpha in the combined analysis.


Though a sailor and a scuba-instructor supposedly are familiar with murcky waters, I guess we would need some statistical consultancy here.

Wist het anker!

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна! 
Helmut Schütz


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Complete thread:

• Meta-analysis earlybird 2010-04-09 07:54 [General Sta­tis­tics] 
  • Meta-analysis in SAS d_labes 2010-04-09 08:35
    • Meta-analysis vs. naïve pooling Helmut 2010-04-09 20:33
      • Meta-analysis vs. naïve pooling ElMaestro 2010-04-09 22:02
        • Meta-analysis vs. naïve pooling Helmut 2010-04-09 22:11
          • Meta-analysis vs. naïve pooling ElMaestro 2010-04-09 22:20
            • Meta-analysis vs. naïve pooling Helmut 2010-04-10 00:49
              • Meta-analysis vs. naïve pooling ElMaestro 2010-04-10 08:13
                • Yes, but...Helmut 2010-04-10 14:46
                  • Yes, but... ElMaestro 2010-04-11 11:44
                    • Yes, but... Helmut 2010-04-11 14:27
      • Meta-analysis alpha d_labes 2010-04-12 13:32
        • Meta-analysis alpha Helmut 2010-04-12 14:25
          • 2-Study Meta-analysis d_labes 2010-04-12 15:03
            • 2-Study Meta-analysis Helmut 2010-04-12 15:18
              • Anatomical miracle d_labes 2010-04-12 15:33
                • Anatomical miracle Helmut 2010-04-12 15:40