Bioequivalence and Bioavailability Forum • Amount

Amount_ Recovered = Ae(0-t) [Software]

posted by Helmut – Vienna, Austria, 2010-04-08 16:27 (5551 d 13:55 ago) – Posting: # 5043
Views: 19,714

Dear AA!

❝ ❝ Please see my suggestion above about your user name. ;-)

❝ ok will change initial to nick name.

Just edit your signature.

❝ What all i understand it is Ae(0-t)is not same as AURClast.

Yes. If extrapolation to t=∞ is not required (what I hope), I would use WinNonlin’s ‘Amount_Recovered’ (Ae_0-t in common PK terminology) for simplicity.

—
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz

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Complete thread:

Pk parameter: Urine study (WinNonlin) AA 2010-04-07 07:01 [Software]
- Ae-inf based on rate Helmut 2010-04-07 18:26
  - Ae-inf based on rate AA 2010-04-08 14:08
    - Amount_ Recovered = Ae(0-t)Helmut 2010-04-08 14:27
  - Already a PK-model? H_Rotter 2010-04-08 20:07
    - Already a PK-model? Helmut 2010-04-08 20:47
      - Dinosaurs solution. d_labes 2010-04-09 09:31
        
        Youngster's solution Helmut 2010-04-09 17:25
        
        Some youngsters may be very old d_labes 2010-04-12 09:39
  - Ae-inf based on rate SDavis 2010-04-09 13:10
    - Replicate design studies in Phoenix/WinNonlin Helmut 2010-04-09 17:47