Philostics [Surveys]
Dear HS,
Thank for this and for the reference. I can learn a lot, and there is a loooooong way to go for me.
I wonder about a issue that is on the border between philosophy and statistics... Analysis of Log Cmax is generally based on the assumption that the residuals are normal. If we subsequently also want to qualify Log Cmin with some kind of statistic can we then conduct such an analysis with parametric statistics? Once we identify Log Cmax we know that the rest will be smaller than that value. Hence, there are constraints on the magnitudes of the residuals in the analysis of Log Cmin and therefore I would be inclined to think we violate an important assumption in parametric statistics?
(I shall abstain from proposing parametric statistics as a potential alternative, notch notch wink wink!)
Best regards,
EM.
Thank for this and for the reference. I can learn a lot, and there is a loooooong way to go for me.
I wonder about a issue that is on the border between philosophy and statistics... Analysis of Log Cmax is generally based on the assumption that the residuals are normal. If we subsequently also want to qualify Log Cmin with some kind of statistic can we then conduct such an analysis with parametric statistics? Once we identify Log Cmax we know that the rest will be smaller than that value. Hence, there are constraints on the magnitudes of the residuals in the analysis of Log Cmin and therefore I would be inclined to think we violate an important assumption in parametric statistics?
(I shall abstain from proposing parametric statistics as a potential alternative, notch notch wink wink!)
Best regards,
EM.
Complete thread:
- Cmin (EU) Helmut 2009-12-21 13:08 [Surveys]
- Cmin (EU) ElMaestro 2009-12-22 14:17
- Terminology issues Helmut 2009-12-22 14:30
- PhilosticsElMaestro 2009-12-27 00:47
- Philostics Helmut 2009-12-27 02:01
- Philostics ElMaestro 2009-12-27 13:28
- Philostics Helmut 2009-12-27 15:07
- Philostics ElMaestro 2009-12-28 02:46
- Philostics Helmut 2009-12-27 15:07
- Philostics ElMaestro 2009-12-27 13:28
- Philostics Helmut 2009-12-27 02:01
- PhilosticsElMaestro 2009-12-27 00:47
- Terminology issues Helmut 2009-12-22 14:30
- Cmin (EU) d_labes 2010-01-04 10:45
- Repeated profiles Helmut 2010-01-04 13:53
- Cmin-value <LLOQ beman 2010-01-04 15:43
- Cmin-value <LLOQ Helmut 2010-01-04 16:34
- Cmin (EU) ElMaestro 2009-12-22 14:17