Bioequivalence and Bioavailability Forum • All the important answers are here!

All the important answers are here! [🇷 for BE/BA]

posted by yjlee168 – Kaohsiung, Taiwan, 2009-09-28 23:30 (5463 d 08:33 ago) – Posting: # 4265
Views: 40,654

Dear Helmut,

I just tried PASS and got the following (for power 70%, T/R=1, CV=7.5%).

Power Analysis of 2x2 Cross-Over Design for Testing Equivalence Using Ratios

Page/Date/Time   1    2009/9/29 03:32:58



Numeric Results for Testing Equivalence Using a Cross-Over Design



                   Lower     Upper

        Total      Equiv.    Equiv.         Coefficient

       Sample      Limit     Limit    True           of

         Size    of Ratio  of Ratio   Ratio   Variation

Power     (N)       (RL)      (RU)    (R1)        (COV)   Alpha    Beta

0.7290     4     0.8000     1.2500   1.0000     0.0750   0.0500  0.2710

0.8434     6     0.8500     1.1765   1.0000     0.0750   0.0500  0.1566

0.7780    10     0.9000     1.1111   1.0000     0.0750   0.0500  0.2220

N = 4. Sorry for my previous message (I set power= 0.8, not 0.7!).

❝ [...]

❝ Do you have one handy?

—
All the best,
-- Yung-jin Lee
bear v2.9.1:- created by Hsin-ya Lee & Yung-jin Lee
Kaohsiung, Taiwan https://www.pkpd168.com/bear
Download link (updated) -> here

Complete thread:

R-Code for Power in 2×2 Cross-over Helmut 2006-12-28 21:33 [🇷 for BE/BA]
- Power in Diletti's sample size table Helmut 2007-01-01 23:59
  - Approximate Power Helmut 2007-01-06 15:17
    - Power Calculation for replicate crossover design mathews 2008-04-03 13:19
      - Power Calculation for replicate crossover design Helmut 2008-04-03 13:49
        
        Power Calculation for replicate crossover design mathews 2008-04-04 13:21
    - Exact Power Helmut 2009-09-25 19:20
      - Exact Power ElMaestro 2009-09-27 23:27
        
        Software validation Helmut 2009-09-28 15:21
        
        All the important answers are here! ElMaestro 2009-09-28 19:12
        
        All the important answers are here! Helmut 2009-09-28 19:52
        
        All the important answers are here! ElMaestro 2009-09-28 20:18
        All the important answers are here!yjlee168 2009-09-28 21:30
        
        All the important answers are here! Helmut 2009-09-28 23:18
        
        42! SASophylistic power oracle d_labes 2009-09-29 13:37
        
        Al Gore Rhythms Helmut 2009-09-29 14:52
        
        Al Gore Rhythms ElMaestro 2009-09-29 18:14
        Al Gore Rhythms yjlee168 2009-09-29 23:55
        
        All the important answers are here! yjlee168 2009-09-29 23:49
- R-Code for Power in 2×2 Cross-over KDA 2019-01-23 04:24
  - R-Code for Power in 2×2 Cross-over Ohlbe 2019-01-27 18:24
- R-Code for Power in 2×2 Cross-over Brus 2021-12-02 15:00
  - R-Code for Power in 2×2 Cross-over ElMaestro 2021-12-02 15:15
    - R-Code for Power in 2×2 Cross-over Helmut 2021-12-02 17:30
  - R-Code for Power in 2×2 Cross-over Helmut 2021-12-02 16:57