Bioequivalence and Bioavailability Forum • Paper, pencil, brain ;-)

Paper, pencil, brain ;-) [Software]

posted by yuvrajkatkar – Pune, Maharashtra (India), 2009-09-21 17:10 (5749 d 04:09 ago) – Posting: # 4224
Views: 28,216

Dear Sir,

Suppose Geometric Least Square Mean Ratio (T/R)=1.20
Lower Confidence Limit=1.08
Upper Confidence Limit=1.33
Number of Subjects (N)=42
Degrees of Freedom=N-2=40;

TINV(.10,40)=1.683851

Based on Lower Confidence Limit
Residual SUMSQ(1.08,1.20)=2.6064
MSresidual=2.6064/40=.06516
and SEdifference=sqrt(2*MSresidual/42)=0.055703296
CVintra=100*SQRT(EXP(MSresidual)-1)=26%

Based on Upper Confidence Limit
Residual SUMSQ(1.33,1.20)=3.2089
MSresidual=3.2089/40=0.0802225
and SEdifference=sqrt(2*MSresidual/42)=0.061807112
CVintra=100*SQRT(EXP(MSresidual)-1)=29%

I want to confirm,
Whether I am right or wrong?

I need your reply.

—
Best Regards,
Yuvraj

Complete thread:

Sample Size Calculation sasikumar 2008-04-03 09:19 [Software]
- Sample Size Calculation (SAS) Jaime_R 2008-04-03 13:13
- Sample Size Calculation d_labes 2008-04-23 11:54
  - Sample Size Calculation balakotu 2009-09-07 07:51
  - Sample Size Calculation yuvrajkatkar 2009-09-19 09:24
    - Paper, pencil, brain ;-) Helmut 2009-09-19 11:48
      - Paper, pencil, brain ;-)yuvrajkatkar 2009-09-21 15:10
        
        Paper, pencil, brain ;-) Helmut 2009-09-21 15:23
        Paper, pencil, brain ;-) Helmut 2009-09-21 18:33
        
        Paper, pencil, brain ;-) yuvrajkatkar 2009-09-22 16:09
        
        No paper, pencil, brain :-( Helmut 2009-09-22 18:22
        
        about your lectures yuvrajkatkar 2009-09-23 07:27
        
        About Trust Helmut 2009-09-23 13:50
        
        sample size calculation yuvrajkatkar 2009-10-01 13:33
        
        inter- / intra- / total variance Helmut 2009-10-01 13:52
        
        inter- / intra- / total variance yuvrajkatkar 2009-10-01 17:13
        
        Theta?! Helmut 2009-10-01 17:30
        
        sample size for parallel design yuvrajkatkar 2009-10-03 07:44
        
        Reference? Helmut 2009-10-03 13:46
        
        MSE obtain from Parallel study in WinNonlin yuvrajkatkar 2009-10-09 16:46
        
        Parallel study in WinNonlin Helmut 2009-10-10 10:51