R2-adj, cut-off [PK / PD]

posted by Helmut Homepage – Vienna, Austria, 2009-04-23 16:39 (5831 d 02:43 ago) – Posting: # 3593
Views: 10,123

Dear Raveendra!

❝ […] what is the minimum R2 value […]. some are using 0.8 and some are using 0.75. which one correct?


Neither nor, because R² depends on the number of data points used in the estimation. In linear regression R² 0.9756 (n=3) ‘explains’ the same amount of information as R² 0.5314 (n=6)!
For a rather lengthy discussion see this thread.
If you truly want to set a cut-off, then R²adj should be used. BTW a cut-off common to all studies is not justified. For drug A a R²adj of 0.95 may be easy to get, whilst for drug B a R²adj of even 0.75 very difficult.

Dif-tor heh smusma 🖖🏼 Довге життя Україна! [image]
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

UA Flag
Activity
 Admin contact
23,422 posts in 4,927 threads, 1,668 registered users;
20 visitors (0 registered, 20 guests [including 11 identified bots]).
Forum time: 19:23 CEST (Europe/Vienna)

To know the history of science is to recognize the mortality
of any claim to universal truth.    Evelyn Fox Keller

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5