Selection of chromatograms and its programme [Bioanalytics]
Dear Pandu,
Selection of 20% chromatograms is done by writing a simple code in SAS by input of the total number of volunteers in the study.
This should be done prior to start of analysis to avoid bias. In this case bioanalytical dept can request the biostatistician to generate a random number, after the randomization is generated it will remain with biostatistician and shared with bioanalytical after the analysis is completed.This will also avoid bias.
For eg the random number generated is 12, and you require 20% of 40 subjects, ideally you select 12-19 subjects serially, but
if any subject is dropout inbetween then select next number e.g if 13 is dropout then select 12 and 14-20.
If the random number itself is dropout then select next number ie from 13-20.
if the random number is generated is last subject number then select for e.g 40 and 1-7.
I hope its clear.
Regards
Chirag
Selection of 20% chromatograms is done by writing a simple code in SAS by input of the total number of volunteers in the study.
This should be done prior to start of analysis to avoid bias. In this case bioanalytical dept can request the biostatistician to generate a random number, after the randomization is generated it will remain with biostatistician and shared with bioanalytical after the analysis is completed.This will also avoid bias.
For eg the random number generated is 12, and you require 20% of 40 subjects, ideally you select 12-19 subjects serially, but
if any subject is dropout inbetween then select next number e.g if 13 is dropout then select 12 and 14-20.
If the random number itself is dropout then select next number ie from 13-20.
if the random number is generated is last subject number then select for e.g 40 and 1-7.
I hope its clear.
Regards
Chirag
Complete thread:
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- Selection of chromatograms and its programme krish3108 2009-03-03 09:10
- Selection of chromatograms and its programme Pandu 2009-02-24 10:16
- 20% of randomly chosen chromatograms Helmut 2009-02-23 15:36