Bioequivalence and Bioavailability Forum

Fieller’s (‘fiducial’) confidence interval [General Statistics]

posted by apapanas – Greece, 2026-03-12 11:54 (92 d 21:09 ago) – Posting: # 24591
Views: 1,681
(edited on 2026-03-12 18:53)

Dear Helmut, dear elmaestro, dear d_labes,

❝ PowerTOST has for this case the functions

❝ - CI.RatioF()

❝ - power.RatioF()

❝ - sampleN.RatioF()

I read your posts with great interest and wondered for the following: If one conducts untransformed PK metric ANOVA analysis and then calculates ratio and 90% Fieller's confidence intervals using the CI.RatioF function, what are the applicable limits – are they still 80–125%?

I would appreciate your advice on this point.
BR
AP

Complete thread:

On CI calculation, untransformed metrics ElMaestro 2019-11-29 03:40 [General Statistics]
- Fieller’s (‘fiducial’) confidence interval Helmut 2019-11-29 10:03
  - Fieller’s (‘fiducial’) confidence interval ElMaestro 2019-11-29 15:53
    - Fieller’s (‘fiducial’) confidence interval d_labes 2019-11-29 17:20
      - Fieller’s (‘fiducial’) confidence interval ElMaestro 2019-11-30 05:11
        
        power.TOST with logscale=FALSE d_labes 2019-11-30 14:01
      - Fieller’s (‘fiducial’) confidence intervalapapanas 2026-03-12 10:54
- On CI calculation, untransformed metrics PharmCat 2019-11-29 12:05

Fieller’s (‘fiducial’) confidence interval [General Sta­tis­tics]

Complete thread:

Fieller’s (‘fiducial’) confidence interval [General Statistics]