Bioequivalence and Bioavailability Forum • lambda

lambda_z estimation [🇷 for BE/BA]

posted by yjlee168 – Kaohsiung, Taiwan, 2008-09-25 23:00 (5683 d 03:24 ago) – Posting: # 2414
Views: 55,646

Dear Ace,

Got it! We'll try it again and will report the result back here soon.
Many thanks.

❝ If the C_max may not be included, this explains the difference between the R code and WinNonlin.

❝ If you change

❝ for (i in (nrow(dat)-3):which.max(dat$conc))

❝ to

❝ for (i in (nrow(dat)-3):(which.max(dat$conc)+1))

❝ then C_max is excluded.

❝

❝ And you would get the same result as WinNonlin.

—
All the best,
-- Yung-jin Lee
bear v2.9.1:- created by Hsin-ya Lee & Yung-jin Lee
Kaohsiung, Taiwan https://www.pkpd168.com/bear
Download link (updated) -> here

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Complete thread:

bear v1.0.0 - a data analytical tool for ABE in R yjlee168 2008-07-12 20:53 [🇷 for BE/BA]
- bear v1.0.0 for R - first impressions Helmut 2008-07-14 04:12
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      - bear v1.0.0 for R - first impressions yjlee168 2008-07-15 09:44
- bear v1.0.0 - a data analytical tool for ABE in R martin 2008-07-14 12:18
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        bear v1.0.0 - a data analytical tool for ABE in R Aceto81 2008-07-16 09:47
        
        bear v1.0.0 - a data analytical tool for ABE in R yjlee168 2008-07-16 21:32
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        TTT method plus best fit combined d_labes 2008-10-01 08:43
        
        AIC or ARS as the best fit criterion? yjlee168 2008-10-02 12:40
        
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        TTT method for lambda_z estimation yjlee168 2008-10-03 21:22
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        bear v1.0.0 - a data analytical tool for ABE in R ElMaestro 2008-07-28 08:42
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        Only balanced, crossover BE studies? ElMaestro 2008-10-24 11:26
        
        Thread locked Helmut 2008-10-24 11:58