simulating dissolution data beyond observed lab data [Dissolution / BCS / IVIVC]

posted by dshah  – India/United Kingdom, 2024-06-10 11:10 (9 d 00:53 ago) – Posting: # 24027
Views: 310

Hi Achievwin,

I agree with Helmut's input.
Further- the assumptions used for extrapolation of modeling, the function/model used used for extrapolation, limitation of used model can be considered on a brief.
Generally, dissolution condition which can fasten the rate of release can be tried for e.g. increasing temperature, rpm, change over media, etc. so that it can be confirmed that the drug release is complete.

Regards,
Divyen

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