CV% and confidence interval [Software]

posted by Darborn – Japan, 2024-05-29 10:26 (21 d 03:09 ago) – Posting: # 24007
Views: 1,145

Hi,

I got a problem related to the CV% (from a parallel BE) and confidence interval. The CV% from winnonlin is ~14% but confidence interval is 74%-136%. Although the sample size for this trial is rather small (19 for analysis), the calculated CV% using confidence interval in PowerTOST is quite large (~39%). I'm not sure why the result is counterintuitive.

Anyone have ideas?

Sincerely,
Jietian

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