## Assumptions (plural) [Design Issues]

Hi Achievwin,

❝ How come we have three different N with same assumptions?

*three*different assumptions.- Uncertain CV → n = 28

- Uncertain T/R-ratio → n = 44

- Uncertain CV and uncertain T/R-ratio → n = 48

*Prior*is important. Play with my example and change the size of the pilot study (*i.e.*, the value`m`

). The smaller, the larger the sample size of the next. Therefore, small pilot studies are not a good idea. It may sound stupid, but the best for sample size estimation is a failed pivotal study… —

Helmut Schütz

The quality of responses received is directly proportional to the quality of the question asked. 🚮

Science Quotes

*Dif-tor heh smusma*🖖🏼 Довге життя Україна!_{}Helmut Schütz

The quality of responses received is directly proportional to the quality of the question asked. 🚮

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### Complete thread:

- Probability of Success in BE studies Achievwin 2024-05-03 13:43 [Design Issues]
- Probability of Success in BE studies Helmut 2024-05-03 14:15
- Probability of Success in BE studies Achievwin 2024-05-06 14:49
- Probability of Success in BE studies d_labes 2024-05-06 15:16
- Probability of Success in BE studies Achievwin 2024-05-06 15:31

- Assumptions (plural)Helmut 2024-05-06 15:31
- Assumptions (plural) Achievwin 2024-05-06 15:51

- Probability of Success in BE studies d_labes 2024-05-06 15:16

- Probability of Success in BE studies Achievwin 2024-05-06 14:49

- Probability of Success in BE studies Helmut 2024-05-03 14:15