Bioequivalence and Bioavailability Forum

❝ Not sure whether I understand you correctly. POS is a Bayesian concept, where you need some prior information.

I am sorry I am equally confused in this example where do we find POS? what all I see is Sample size and anticipated power with certain N.

How come we have three different N with same assumptions?

❝ As usual, the T/R-ratio is the killer.

----- Thanks for reiterating my thought all along many of my colleagues are having issue in understanding T/R is main culprit than ISCV in Sample size estimates.

Please edcuate me on how to connect Power with POS?

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Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5! [Helmut]