Probability of Success in BE studies [Design Issues]
Recently I was asked to give Probability of success for a proposed BE study, My thinking is Target study power (usually 80%) is POS with additional correction factor due to the variability during study conduct applied to this target power, is my understanding correct?
Challenge is that do you substract or a multiply the variability factor?
e.g. POS = Target Power (90) - 30 (CV)= 60 0r 90X(1-0.30)=63%
Achievwin
Challenge is that do you substract or a multiply the variability factor?
e.g. POS = Target Power (90) - 30 (CV)= 60 0r 90X(1-0.30)=63%
Achievwin
Complete thread:
- Probability of Success in BE studiesAchievwin 2024-05-03 13:43 [Design Issues]
- Probability of Success in BE studies Helmut 2024-05-03 14:15
- Probability of Success in BE studies Achievwin 2024-05-06 14:49
- Probability of Success in BE studies d_labes 2024-05-06 15:16
- Probability of Success in BE studies Achievwin 2024-05-06 15:31
- Assumptions (plural) Helmut 2024-05-06 15:31
- Assumptions (plural) Achievwin 2024-05-06 15:51
- Probability of Success in BE studies d_labes 2024-05-06 15:16
- Probability of Success in BE studies Achievwin 2024-05-06 14:49
- Probability of Success in BE studies Helmut 2024-05-03 14:15