power.TOST.sim code [Outliers]

posted by mittyri – Russia, 2023-10-31 16:40 (28 d 16:20 ago) – Posting: # 23770
Views: 580

Dear BEQool!

❝ Distributions (both normal and log-normal) are determined by their mean and variance. As discussed above, in order to get power we need distribution of PE; the mean is of course PE but what about the variance? Is the variance of PE distribution MSE? Or something else?

I think it is better to look into the code

  # simulate point est. via normal distribution
  pes   <- rnorm(n=nsims, mean=diffm, sd=se.fac*sqrt(mse))
  # simulate mse via chi-squared distribution
  mses  <- mse*rchisq(n=nsims, df=df)/df

So the variance is calculated based on MSE, design constant and the number of subjects:
power.TOST.sim <- function(<...>) {
  d.no  <- .design.no(design)
  ades  <- .design.props(d.no)
  nc <- sum(1/n)
  se.fac <- sqrt(ades$bkni * nc)

Kind regards,

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