carry over effect investigation based on what? [General Sta­tis­tics]

posted by dshah  – India, 2023-10-06 15:20 (347 d 03:38 ago) – Posting: # 23746
Views: 3,080

Hi Helmut & Mittyri!


❝ I agree with what Mittyri wrote above. Is is possible that you mixed it up with the 20% of subjects with extrapolated AUC >20%?


Yes, Probability I may have mixed up the things.
But with carry over effect, there is high probability that the subject would not have ratio of AUCt/AUCinf>0.8? which can be due to insufficient washout period? So there is high chance that where carry over is observed, the AUCt/AUCinf> 0.8 is not achieved and thus the investigation on this.

Complete thread:

UA Flag
Activity
 Admin contact
23,226 posts in 4,879 threads, 1,657 registered users;
41 visitors (0 registered, 41 guests [including 10 identified bots]).
Forum time: 18:59 CEST (Europe/Vienna)

The real purpose of the scientific method is to make sure
nature hasn’t misled you into thinking you know something
you actually don’t know.    Robert M. Pirsig

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5