carry over effect investigation based on what? [General Statistics]
Hi Helmut & Mittyri!
Yes, Probability I may have mixed up the things.
But with carry over effect, there is high probability that the subject would not have ratio of AUCt/AUCinf>0.8? which can be due to insufficient washout period? So there is high chance that where carry over is observed, the AUCt/AUCinf> 0.8 is not achieved and thus the investigation on this.
❝ I agree with what Mittyri wrote above. Is is possible that you mixed it up with the 20% of subjects with extrapolated AUC >20%?
Yes, Probability I may have mixed up the things.
But with carry over effect, there is high probability that the subject would not have ratio of AUCt/AUCinf>0.8? which can be due to insufficient washout period? So there is high chance that where carry over is observed, the AUCt/AUCinf> 0.8 is not achieved and thus the investigation on this.
Complete thread:
- Carry over and statistical adjustment in BE computations Achievwin 2023-10-02 20:34 [General Statistics]
- Carry-over → 🚮 Helmut 2023-10-02 21:06
- Carry-over → 🚮 Achievwin 2023-10-03 12:13
- Carry-over → 🚮 Helmut 2023-10-03 12:48
- Carry-over dshah 2023-10-03 16:34
- Carry-over Achievwin 2023-10-03 20:33
- Carry-over Helmut 2023-10-04 08:31
- Carry-over Achievwin 2023-10-04 16:38
- Carry-over dshah 2023-10-04 11:22
- Carry-over Helmut 2023-10-04 08:31
- more than 20% subject carry over effect investigation mittyri 2023-10-05 20:15
- carry over effect investigation based on what? Helmut 2023-10-06 07:08
- carry over effect investigation based on what?dshah 2023-10-06 13:20
- Carry-over Achievwin 2023-10-03 20:33
- Carry-over → 🚮 Achievwin 2023-10-03 12:13
- Outdated and wrong answers mittyri 2023-10-05 20:34
- Wrong answer Helmut 2023-10-06 07:19
- Carry-over → 🚮 Helmut 2023-10-02 21:06