Outdated and wrong answers [General Statistics]
Dear Achievewin!
15-20 years ago the answers could be the following
Please don't get me wrong. These answers could be correct decades ago.
15-20 years ago the answers could be the following
- How to measure carry-over (any particular PK parameters or in vitro measures?)
Usually we say that unequal carryover exists, when the p-value for Sequence effect in ANOVA is less than 5% for any of parameters of interest.
We say that equal carryover exists, when the p-value for Period effect in ANOVA is less than 5%.
- How to assess equal or unequal carryover?
See above
- Differences in 1st order or other order carry-over
Something like this (one carryover effect overrides the previous one)
https://online.stat.psu.edu/stat509/lesson/15/15.5
- Is there a cut-off to call negligible carry-over
If the sequence effect is more than 5%: the carry-over effect is negligible.
- What are the statistical tests to call it a unequal carry-over or no un-equal carry-over.
ANOVA F test
- How to factor or apply any corrections of observed carry-over in BE and RSABE calculations?
Apply BE for the 1st period only.
Please don't get me wrong. These answers could be correct decades ago.
—
Kind regards,
Mittyri
Kind regards,
Mittyri
Complete thread:
- Carry over and statistical adjustment in BE computations Achievwin 2023-10-02 20:34 [General Statistics]
- Carry-over → 🚮 Helmut 2023-10-02 21:06
- Carry-over → 🚮 Achievwin 2023-10-03 12:13
- Carry-over → 🚮 Helmut 2023-10-03 12:48
- Carry-over dshah 2023-10-03 16:34
- Carry-over Achievwin 2023-10-03 20:33
- Carry-over Helmut 2023-10-04 08:31
- Carry-over Achievwin 2023-10-04 16:38
- Carry-over dshah 2023-10-04 11:22
- Carry-over Helmut 2023-10-04 08:31
- more than 20% subject carry over effect investigation mittyri 2023-10-05 20:15
- carry over effect investigation based on what? Helmut 2023-10-06 07:08
- carry over effect investigation based on what? dshah 2023-10-06 13:20
- Carry-over Achievwin 2023-10-03 20:33
- Carry-over → 🚮 Achievwin 2023-10-03 12:13
- Outdated and wrong answersmittyri 2023-10-05 20:34
- Wrong answer Helmut 2023-10-06 07:19
- Carry-over → 🚮 Helmut 2023-10-02 21:06