Outdated and wrong answers [General Sta­tis­tics]

posted by mittyri – Russia, 2023-10-05 22:34 (66 d 12:28 ago) – Posting: # 23743
Views: 986

Dear Achievewin!

15-20 years ago the answers could be the following
  1. How to measure carry-over (any particular PK parameters or in vitro measures?)
    Usually we say that unequal carryover exists, when the p-value for Sequence effect in ANOVA is less than 5% for any of parameters of interest.
    We say that equal carryover exists, when the p-value for Period effect in ANOVA is less than 5%.

  2. How to assess equal or unequal carryover?
    See above

  3. Differences in 1st order or other order carry-over

    Something like this (one carryover effect overrides the previous one)

  4. Is there a cut-off to call negligible carry-over
    If the sequence effect is more than 5%: the carry-over effect is negligible.

  5. What are the statistical tests to call it a unequal carry-over or no un-equal carry-over.
    ANOVA F test

  6. How to factor or apply any corrections of observed carry-over in BE and RSABE calculations?
    Apply BE for the 1st period only.

Please don't get me wrong. These answers could be correct decades ago.

Kind regards,

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