Bioequivalence and Bioavailability Forum

more than 20% subject carry over effect investigation [General Statistics]

posted by mittyri – Russia, 2023-10-05 22:15 (986 d 04:11 ago) – Posting: # 23742
Views: 12,933

Dear Divyen!

❝ If more than 20% subject has carry over effect (more than 5%Cmax value), than an investigation would be needed but this indicates that washout period was insufficient.

Could you please enlighten me - why 20%? Why 15% could not trigger investigation? Are 15% not enough to start investigation?

—
Kind regards,
Mittyri

Complete thread:

Carry over and statistical adjustment in BE computations Achievwin 2023-10-02 20:34 [General Statistics]
- Carry-over → 🚮 Helmut 2023-10-02 21:06
  - Carry-over → 🚮 Achievwin 2023-10-03 12:13
    - Carry-over → 🚮 Helmut 2023-10-03 12:48
    - Carry-over dshah 2023-10-03 16:34
      - Carry-over Achievwin 2023-10-03 20:33
        
        Carry-over Helmut 2023-10-04 08:31
        
        Carry-over Achievwin 2023-10-04 16:38
        
        Carry-over dshah 2023-10-04 11:22
      - more than 20% subject carry over effect investigationmittyri 2023-10-05 20:15
      - carry over effect investigation based on what? Helmut 2023-10-06 07:08
        
        carry over effect investigation based on what? dshah 2023-10-06 13:20
    - Carry-over → 🚮 Mahmoud 2025-12-09 10:47
      - Carry-over → 🚮 Helmut 2025-12-10 10:38
        
        Carry-over → 🚮 Mahmoud 2025-12-11 05:11
- Outdated and wrong answers mittyri 2023-10-05 20:34
  - Wrong answer Helmut 2023-10-06 07:19

more than 20% subject carry over effect investigation [General Sta­tis­tics]

Complete thread:

more than 20% subject carry over effect investigation [General Statistics]