Bioequivalence and Bioavailability Forum

Carry-over [General Statistics]

posted by dshah – India, 2023-10-04 13:22 (988 d 12:29 ago) – Posting: # 23738
Views: 12,827

Hi AchievWin!

❝ <5% of Cmax rule is not applied (this is a news for me)

Any example-Pls give me? As suggested by Helmut- if you are talking about endogenous substance, then the base line correction method would play a significant role.

Honestly, I have seen some carry over- but the protocol does take care of it.
Can you share the protocol's inclusion/exclusion criteria for PK/stat part?

Regards,
Divyen

Complete thread:

Carry over and statistical adjustment in BE computations Achievwin 2023-10-02 20:34 [General Statistics]
- Carry-over → 🚮 Helmut 2023-10-02 21:06
  - Carry-over → 🚮 Achievwin 2023-10-03 12:13
    - Carry-over → 🚮 Helmut 2023-10-03 12:48
    - Carry-over dshah 2023-10-03 16:34
      - Carry-over Achievwin 2023-10-03 20:33
        
        Carry-over Helmut 2023-10-04 08:31
        
        Carry-over Achievwin 2023-10-04 16:38
        
        Carry-overdshah 2023-10-04 11:22
      - more than 20% subject carry over effect investigation mittyri 2023-10-05 20:15
      - carry over effect investigation based on what? Helmut 2023-10-06 07:08
        
        carry over effect investigation based on what? dshah 2023-10-06 13:20
    - Carry-over → 🚮 Mahmoud 2025-12-09 10:47
      - Carry-over → 🚮 Helmut 2025-12-10 10:38
        
        Carry-over → 🚮 Mahmoud 2025-12-11 05:11
- Outdated and wrong answers mittyri 2023-10-05 20:34
  - Wrong answer Helmut 2023-10-06 07:19

Carry-over [General Sta­tis­tics]

Complete thread:

Carry-over [General Statistics]