Bioequivalence and Bioavailability Forum

Carry-over [General Statistics]

posted by Achievwin – US, 2023-10-03 22:33 (589 d 03:39 ago) – Posting: # 23736
Views: 5,051

Dear Divyan and Helmut:

Whether we like it or not this question keep popping, can you both or anyone answer my questions above (I have views but I want to hear what other alternatives are there - my views align mostly with Helmut view but.... regulators are regulators)

I am struggling with the basic question how to quantify carry-over? and for some products that <5% of Cmax rule is not applied (this is a news for me)

Thanks a lot

AchievWin

Complete thread:

Carry over and statistical adjustment in BE computations Achievwin 2023-10-02 20:34 [General Statistics]
- Carry-over → 🚮 Helmut 2023-10-02 21:06
  - Carry-over → 🚮 Achievwin 2023-10-03 12:13
    - Carry-over → 🚮 Helmut 2023-10-03 12:48
    - Carry-over dshah 2023-10-03 16:34
      - Carry-overAchievwin 2023-10-03 20:33
        
        Carry-over Helmut 2023-10-04 08:31
        
        Carry-over Achievwin 2023-10-04 16:38
        
        Carry-over dshah 2023-10-04 11:22
      - more than 20% subject carry over effect investigation mittyri 2023-10-05 20:15
      - carry over effect investigation based on what? Helmut 2023-10-06 07:08
        
        carry over effect investigation based on what? dshah 2023-10-06 13:20
- Outdated and wrong answers mittyri 2023-10-05 20:34
  - Wrong answer Helmut 2023-10-06 07:19

Carry-over [General Sta­tis­tics]

Complete thread:

Carry-over [General Statistics]