tmax ≠ Cmax 🙂 [NCA / SHAM]

posted by Imph – 2023-06-27 19:33 (335 d 01:50 ago) – Posting: # 23630
Views: 1,425

❝ ❝ Tmax: Time of maximum observed concentration. For non-steady-state data, the entire curve is considered. If the maximum observed concentration is not unique, then the first maximum is used


❝ Sure, but you were talking about Cmax – not tmax. That’s how it is implemented in all software I know.


Yes but the Cmax was defined accordingly:

Cmax: Maximum observed concentration, occurring at time Tmax, as defined above.

When reading this, we can easily think that the software would take the first peak as Cmax.


Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5[Helmut]

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