## No ‘R1’ and ‘R2’ in replicate designs [General Statistics]

Sorry, because I am lego and I can´t understand all correctly.

❝ There is no ‘R** _{1}**’ and ‘R

**’, only**

_{2}*one*R repeatedly administered in the sequences in different periods. Say, the sequences are

`TRR | RTR | RRT`

. Did the CRO *call*the first administration in each sequence R

_{1}and the second R

_{2}(while dropping T)?

❝ As said above, such a ‘comparison’ will not work.

❝ You tried `CI2CV(lower=0.8731, upper=1.4057, design="2x2x2", n=40)`

, right? That’s not what you have. After recoding (wild guess) you have an Incomplete Block Design. Other degrees of freedom,

❝ These formulas are for a 2×2×2 crossover and are also implemented in `CI2CV()`

. But again, there is only *one* R. A ‘PE’ and ‘CI’ doesn’t make sense.

❝ You can only calculate the *CV*_{wR} according to the EMA’s or the FDA’s models. The results will be similar, though quite often the one of the FDA is a bit smaller.

Edit: Standard quotes restored; see also this post #8. [Helmut]

### Complete thread:

- Calculation of PE and 90% CI Brus 2023-06-14 16:34 [General Statistics]
- No ‘R1’ and ‘R2’ in replicate designs Helmut 2023-06-14 22:26
- No ‘R1’ and ‘R2’ in replicate designsBrus 2023-06-15 14:07
- Rose is a rose is a rose is a rose Helmut 2023-06-15 14:49
- No ‘R1’ and ‘R2’ in replicate designs Achievwin 2023-06-19 19:42

- No ‘R1’ and ‘R2’ in replicate designsBrus 2023-06-15 14:07

- No ‘R1’ and ‘R2’ in replicate designs Helmut 2023-06-14 22:26