Bioequivalence and Bioavailability Forum

within subject standard deviation in fully replicate design if carry over effect is present [General Sta­tis­tics]

posted by dshah  – India, 2023-06-14 12:37 (673 d 21:04 ago) – Posting: # 23591
Views: 2,837

Hello Ankit!

As per PSG, the recommendation is parallel study.

❝ So how to calculate Swr when unequal carryover effect is present in full replicate study design?

Moreover, the study population is patient and you can not stop the treatment. So why fully replicate CO study?

Regards,
Divyen

Complete thread:

• within subject stan­dard devi­ation in fully repli­cate design if carry over effect is pre­sent Ankit Parikh 2023-06-08 13:54 [General Sta­tis­tics] 
  • within subject standard deviation in fully replicate design if carry over effect is present dshah 2023-06-08 16:35
    • within subject standard deviation in fully replicate design if carry over effect is present Ankit Parikh 2023-06-09 07:15
      • within subject standard deviation in fully replicate design if carry over effect is present dshah 2023-06-14 09:26
        • within subject standard deviation in fully replicate design if carry over effect is present Ankit Parikh 2023-06-14 09:33
          • within subject standard deviation in fully replicate design if carry over effect is presentdshah 2023-06-14 10:37