within subject standard deviation in fully replicate design if carry over effect is present [General Sta­tis­tics]

posted by dshah  – India/United Kingdom, 2023-06-08 18:35 (115 d 11:03 ago) – Posting: # 23583
Views: 721

Hello Ankit!

❝ After dosing, the plasma concentration reaches Cmax in about 4 hours and comes down below 5 % of Cmax in 2-3 days and remains stable from day 4 to 120 and is also the pre-dose concentration for subsequent period/s.

I am not getting you. By 2-3 days, the concentration are below 5% of Cmax and then stable from day 4 to 120?
So by 2-3 days, almost all the drug is eliminated? What is the average half life and range of half life for drug?


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