Bioequivalence and Bioavailability Forum

within subject standard deviation in fully replicate design if carry over effect is present [General Statistics]

posted by dshah – India/United Kingdom, 2023-06-08 18:35 (115 d 11:03 ago) – Posting: # 23583
Views: 721

Hello Ankit!

❝ After dosing, the plasma concentration reaches Cmax in about 4 hours and comes down below 5 % of Cmax in 2-3 days and remains stable from day 4 to 120 and is also the pre-dose concentration for subsequent period/s.

I am not getting you. By 2-3 days, the concentration are below 5% of Cmax and then stable from day 4 to 120?
So by 2-3 days, almost all the drug is eliminated? What is the average half life and range of half life for drug?

Regards,
Divyen

Complete thread:

within subject standard deviation in fully replicate design if carry over effect is present Ankit Parikh 2023-06-08 13:54 [General Statistics]
- within subject standard deviation in fully replicate design if carry over effect is presentdshah 2023-06-08 16:35
  - within subject standard deviation in fully replicate design if carry over effect is present Ankit Parikh 2023-06-09 07:15
    - within subject standard deviation in fully replicate design if carry over effect is present dshah 2023-06-14 09:26
      - within subject standard deviation in fully replicate design if carry over effect is present Ankit Parikh 2023-06-14 09:33
        
        within subject standard deviation in fully replicate design if carry over effect is present dshah 2023-06-14 10:37

within subject standard deviation in fully replicate design if carry over effect is present [General Sta­tis­tics]

Complete thread:

within subject standard deviation in fully replicate design if carry over effect is present [General Statistics]