Bioequivalence and Bioavailability Forum

❝ 74.02% (90% CI: 65.69–83.41%) is correct. Confirmed in Phoenix/WinNonlin, R, and ‘manually’ in a spreadsheet. See BEQool’s post above for the likely explanation.

❝ I don’t speak SAS; try to remove to dollar-characters from the headers in your data statement.

Thanks all for your replying.

1. I accidentally put "weiguo2122$2gmail.com" as my username, now it is hard to make a change because "edit profile" do not allow me make change". If possible, please change my username as "Weiguo21224" at your end.

2. I carefully reviewed previous discussion. My understanding is that "T" and "R" in FDA code do represent the "Test drug" and "Reference drug" respectively. It should be:

ESTIMATE 'T (the large/later one in lexical order, Reference drug) vs. R (the small/early one in lexical order, Test drug') TRT 1 -1/CL ALPHA=0.1;

Right?

Best!

David

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Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post #5! [Helmut]