Bioequivalence and Bioavailability Forum • Higher-Order Crossovers

Higher-Order Crossovers [Power / Sample Size]

posted by Helmut – Vienna, Austria, 2023-04-20 12:19 (364 d 14:40 ago) – Posting: # 23530
Views: 2,313

Hi BEQool,

❝ ❝ ❝ From a 2×2×2 crossover design we may estimate :blahblah:

❝ And since it was mentioned that we may estimate CVs with these equations from a 2x2x2 crossover study I am curious if this equations for CVs also apply for other higher order designs?

Yes. I strongly suggest to follow the ‘Two at a Time’-approach instead of an ANOVA of pooled data (see there).

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Complete thread:

Sample size estimation for parallel design Nav Coelho 2007-07-20 16:14 [Power / Sample Size]
- Parallel designs (total variance) Helmut 2007-07-20 16:29
  - Parallel designs (total variance) Nav Coelho 2007-07-20 18:38
    - CV-intra # 60% CV-inter Helmut 2007-07-22 01:17
    - total (pooled) variance: examples Helmut 2007-07-23 17:44
      - total (pooled) variance: examples Nav Coelho 2007-07-23 19:58
      - total (pooled) variance: examples BEQool 2023-04-18 09:59
        
        Higher-Order CrossoversHelmut 2023-04-20 10:19
        
        Higher-Order Crossovers BEQool 2023-04-21 07:53
        
        total (pooled) variance: examples zizou 2023-04-21 21:23
        
        total (pooled) variance: examples BEQool 2023-04-22 18:20
        
        total (pooled) variance: examples zizou 2023-04-22 21:06
        
        total (pooled) variance: examples BEQool 2023-04-25 10:57
        
        total (pooled) variance: examples zizou 2023-04-25 22:43
        
        total (pooled) variance: examples BEQool 2023-05-04 08:17
- Sample size estimation for parallel design Dipesh Jayswal 2007-07-24 08:52