Definition of Full Replicate [Design Issues]

posted by Achievwin – US, 2023-03-27 21:08 (388 d 12:53 ago) – Posting: # 23513
Views: 2,428

Dear Experts

Can TRT, RTR be called two sequence full replicate in three way cross over? can it be a substitute for RTRT or TRTR, or TTRR or RRTT (in four period fully replicated design)?

The goal is to do a 3-period cross-over yet to capture ISCV for Test and Reference separately. Can this type of design address RSABE for warfarin by FDA?

(Nothing) Achievwin:-D:confused:

Complete thread:

UA Flag
Activity
 Admin contact
22,987 posts in 4,824 threads, 1,663 registered users;
84 visitors (0 registered, 84 guests [including 4 identified bots]).
Forum time: 10:02 CEST (Europe/Vienna)

The only way to comprehend what mathematicians mean by Infinity
is to contemplate the extent of human stupidity.    Voltaire

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5